64 citations · 192 across the 6 of their papers we have counts for
6 papers
Measurement of work in single-molecule experiments
Alessandro Mossa, Sara de Lorenzo, Josep Maria Huguet +1
A main goal of single-molecule experiments is to evaluate equilibrium free energy differences by applying fluctuation relations to repeated work measurements along irreversible pro…
Dynamic force spectroscopy of DNA hairpins. II. Irreversibility and dissipation
Maria Manosas, Alessandro Mossa, Nuria Forns +2
We investigate irreversibility and dissipation in single molecules that cooperatively fold/unfold in a two state manner under the action of mechanical force. We apply path thermody…
Dynamic force spectroscopy of DNA hairpins. I. Force kinetics and free energy landscapes
Alessandro Mossa, Maria Manosas, Nuria Forns +2
We investigate the thermodynamics and kinetics of DNA hairpins that fold/unfold under the action of applied mechanical force. We introduce the concept of the molecular free energy…
Recovery of free energy branches in single molecule experiments
Ivan Junier, Alessandro Mossa, Maria Manosas +1
We present a method for determining the free energy of coexisting states from irreversible work measurements. Our approach is based on a fluctuation relation that is valid for diss…
Supersymmetric Langevin equation to explore free energy landscapes
Alessandro Mossa, Cecilia Clementi
The recently discovered supersymmetric generalizations of Langevin dynamics and Kramers equation can be utilized for the exploration of free energy landscapes of systems whose larg…
Hamiltonian dynamics of homopolymer chain models
Alessandro Mossa, Marco Pettini, Cecilia Clementi
The Hamiltonian dynamics of chains of nonlinearly coupled particles is numerically investigated in two and three dimensions. Simple, off-lattice homopolymer models are used to repr…