510 citations
- University of EdinburghGB26 papers
- Edinburgh GenomicsGB3 papers
- UK Astronomy Technology CentreGB3 papers
- University of BergenNO3 papers
- Biomathematics and Statistics ScotlandGB2 papers
- Curtin UniversityAU2 papers
- Heriot-Watt UniversityGB2 papers
- International Centre for Radio Astronomy ResearchAU2 papers
- Karolinska InstitutetSE2 papers
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- The Queen's Medical Research InstituteGB2 papers
- University of California, DavisUS2 papers
4 papers · 1 filter
Integrative multi-omics module network inference with Lemon-Tree
Eric Bonnet, Laurence Calzone, Tom Michoel
Module network inference is an established statistical method to reconstruct co-expression modules and their upstream regulatory programs from integrated multi-omics datasets measu…
A scalable method for molecular network reconstruction identifies properties of targets and mutations in acute myeloid leukemia
Edison Ong, Anthony Szedlak, Yunyi Kang +9
A key aim of systems biology is the reconstruction of molecular networks, however we do not yet have networks that integrate information from all datasets available for a particula…
Multi-species network inference improves gene regulatory network reconstruction for early embryonic development in Drosophila
Anagha Joshi, Yvonne Beck, Tom Michoel
Gene regulatory network inference uses genome-wide transcriptome measurements in response to genetic, environmental or dynamic perturbations to predict causal regulatory influences…
Natural coordinate descent algorithm for L1-penalised regression in generalised linear models
Tom Michoel
The problem of finding the maximum likelihood estimates for the regression coefficients in generalised linear models with an L1 sparsity penalty is shown to be equivalent to minimi…