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stat.ME2010★ 302 cited
Replication in Genome-Wide Association Studies
Peter Kraft, Eleftheria Zeggini, John P. A. Ioannidis
Replication helps ensure that a genotype-phenotype association observed in a genome-wide association (GWA) study represents a credible association and is not a chance finding or an…
stat.ME2010★ 19 cited
A Bayesian Method for Detecting and Characterizing Allelic Heterogeneity and Boosting Signals in Genome-Wide Association Studies
Zhan Su, Niall Cardin, the Wellcome Trust Case Control Consortium +2
The standard paradigm for the analysis of genome-wide association studies involves carrying out association tests at both typed and imputed SNPs. These methods will not be optimal…