activity
20122022
most citedCellular compartments cause multistability in biochemical reaction networks and allow cells to process more information

8 citations · 20 across the 10 of their papers we have counts for

collaborators

17 papers

q-bio.NC2022

Barcodes distinguish morphology of neuronal tauopathy

David Beers, Despoina Goniotaki, Diane P. Hanger +2

The geometry of neurons is known to be important for their functions. Hence, neurons are often classified by their morphology. Two recent methods, persistent homology and the topol…

math.AT2022

Homology of homologous knotted proteins

Katherine Benjamin, Lamisah Mukta, Gabriel Moryoussef +4

Quantification and classification of protein structures, such as knotted proteins, often requires noise-free and complete data. Here we develop a mathematical pipeline that systema…

q-bio.QM2021

Topological Approximate Bayesian Computation for Parameter Inference of an Angiogenesis Model

Thomas Thorne, Paul D. W. Kirk, Heather A. Harrington

Inferring the parameters of models describing biological systems is an important problem in the reverse engineering of the mechanisms underlying these systems. Much work has focuse…

q-bio.QM2021

Topological data analysis distinguishes parameter regimes in the Anderson-Chaplain model of angiogenesis

John T. Nardini, Bernadette J. Stolz, Kevin B. Flores +2

Angiogenesis is the process by which blood vessels form from pre-existing vessels. It plays a key role in many biological processes, including embryonic development and wound heali…

q-bio.BM2019

Grid diagrams as tools to investigate knot spaces and topoisomerase-mediated simplification of DNA topology

Agnese Barbensi, Daniele Celoria, Heather A. Harrington +2

Grid diagrams with their relatively simple mathematical formalism provide a convenient way to generate and model projections of various knots. It has been an open question whether…

q-bio.QM20195 cited

Topological Methods for Characterising Spatial Networks: A Case Study in Tumour Vasculature

Helen M Byrne, Heather A Harrington, Ruth Muschel +3

Understanding how the spatial structure of blood vessel networks relates to their function in healthy and abnormal biological tissues could improve diagnosis and treatment for dise…