206 citations · 835 across the 12 of their papers we have counts for
12 papers
Sensitivity of small myosin II ensembles from different isoforms to mechanical load and ATP concentration
Thorsten Erdmann, Kathrin Bartelheimer, Ulrich S. Schwarz
Based on a detailed crossbridge model for individual myosin II motors, we systematically study the influence of mechanical load and adenosine triphosphate (ATP) concentration on sm…
Stochastic dynamics and mechanosensitivity of myosin II minifilaments
Philipp J. Albert, Thorsten Erdmann, Ulrich S. Schwarz
Tissue cells are in a state of permanent mechanical tension that is maintained mainly by myosin II minifilaments, which are bipolar assemblies of tens of myosin II molecular motors…
Stochastic dynamics of small ensembles of non-processive molecular motors: the parallel cluster model
Thorsten Erdmann, Philipp J. Albert, Ulrich S. Schwarz
Non-processive molecular motors have to work together in ensembles in order to generate appreciable levels of force or movement. In skeletal muscle, for example, hundreds of myosin…
Mutual Repression enhances the Steepness and Precision of Gene Expression Boundaries
Thomas R. Sokolowski, Thorsten Erdmann, Pieter Rein ten Wolde
Embryonic development is driven by spatial patterns of gene expression that determine the fate of each cell in the embryo. While gene expression is often highly erratic, embryonic…
Stochastic force generation by small ensembles of myosin II motors
Thorsten Erdmann, Ulrich S. Schwarz
Forces in the actin cytoskeleton are generated by small groups of non-processive myosin II motors for which stochastic effects are highly relevant. Using a crossbridge model with t…
The role of spatial averaging in the precision of gene expression patterns
Thorsten Erdmann, Martin Howard, Pieter Rein ten Wolde
During embryonic development, differentiating cells respond via gene expression to positional cues from morphogen gradients. While gene expression is often highly erratic, embryoni…