510 citations · 2.4k across the 88 of their papers we have counts for
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Stochastic dynamics and ribosome-RNAP interactions in Transcription-Translation Coupling
Xiangting Li, Tom Chou
Under certain cellular conditions, transcription and mRNA translation in prokaryotes appear to be "coupled," in which the formation of mRNA transcript and production of its associa…
A mathematical model of reward-mediated learning in drug addiction
Tom Chou, Maria D'Orsogna
Substances of abuse are known to activate and disrupt neuronal circuits in the brain reward system. We propose a simple and easily interpretable dynamical systems model to describe…
Mathematical Characterization of Private and Public Immune Repertoire Sequences
Lucas Böttcher, Sascha Wald, Tom Chou
Diverse T and B cell repertoires play an important role in mounting effective immune responses against a wide range of pathogens and malignant cells. The number of unique T and B c…
Adaptive Hermite Spectral Methods in Unbounded Domains
Tom Chou, Sihong Shao, Mingtao Xia
Recently, new adaptive techniques were developed that greatly improved the efficiency of solving PDEs using spectral methods. These adaptive spectral techniques are especially suit…
Spectrally Adapted Physics-Informed Neural Networks for Solving Unbounded Domain Problems
Mingtao Xia, Lucas Böttcher, Tom Chou
Solving analytically intractable partial differential equations (PDEs) that involve at least one variable defined on an unbounded domain arises in numerous physical applications. A…