510 citations · 2.4k across the 88 of their papers we have counts for
88 papers
Forecasting drug overdose mortality by age in the United States at the national and county levels
Lucas Böttcher, Tom Chou, Maria R. D'Orsogna
The drug overdose crisis in the United States continues to intensify. Fatalities have increased five-fold since 1999 reaching a record high of 108,000 deaths in 2021. The epidemic…
Modeling and forecasting age-specific drug overdose mortality in the United States
Lucas Böttcher, Tom Chou, Maria R. D'Orsogna
Drug overdose deaths continue to increase in the United States for all major drug categories. Over the past two decades the total number of overdose fatalities has increased more t…
Overcompensation of transient and permanent death rate increases in age-structured models with cannibalistic interactions
Mingtao Xia, Xiangting Li, Tom Chou
There has been renewed interest in understanding the mathematical structure of ecological population models that lead to overcompensation, the process by which a population recover…
Impact of random and targeted disruptions on information diffusion during outbreaks
Hosein Masoomy, Tom Chou, Lucas Böttcher
Outbreaks are complex multi-scale processes that are impacted not only by cellular dynamics and the ability of pathogens to effectively reproduce and spread, but also by population…
Stochastic dynamics and ribosome-RNAP interactions in Transcription-Translation Coupling
Xiangting Li, Tom Chou
Under certain cellular conditions, transcription and mRNA translation in prokaryotes appear to be "coupled," in which the formation of mRNA transcript and production of its associa…
A mathematical model of reward-mediated learning in drug addiction
Tom Chou, Maria D'Orsogna
Substances of abuse are known to activate and disrupt neuronal circuits in the brain reward system. We propose a simple and easily interpretable dynamical systems model to describe…