510 citations · 2.4k across the 88 of their papers we have counts for
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Controlling epidemics through optimal allocation of test kits and vaccine doses across networks
Mingtao Xia, Lucas Böttcher, Tom Chou
Efficient testing and vaccination protocols are critical aspects of epidemic management. To study the optimal allocation of limited testing and vaccination resources in a heterogen…
A statistical model of COVID-19 testing in populations: effects of sampling bias and testing errors
Lucas Böttcher, Maria R. D'Orsogna, Tom Chou
We develop a statistical model for the testing of disease prevalence in a population. The model assumes a binary test result, positive or negative, but allows for biases in sample…
Density- and elongation speed-dependent error correction in RNA polymerization
Xinzhe Zuo, Tom Chou
Backtracking of RNA polymerase (RNAP) is an important pausing mechanism during DNA transcription that is part of the error correction process that enhances transcription fidelity.…
Kinetic theory for structured populations: application to stochastic sizer-timer models of cell proliferation
Mingtao Xia, Tom Chou
We derive the full kinetic equations describing the evolution of the probability density distribution for a structured population such as cells distributed according to their ages…
Using excess deaths and testing statistics to improve estimates of COVID-19 mortalities
Lucas Böttcher, Maria D'Orsogna, Tom Chou
Factors such as non-uniform definitions of mortality, uncertainty in disease prevalence, and biased sampling complicate the quantification of fatality during an epidemic. Regardles…