activity
20012025
most citedViral self-assembly as a thermodynamic process

200 citations · 1.5k across the 55 of their papers we have counts for

collaborators

55 papers

cond-mat.soft2025

An Assembly-Line Mechanism for In-Vitro Encapsulation of Fragmented Cargo in Virus-Like Particles

Ayesha Amjad, Irina Tsvetkova, Lena G. Lowry +4

The ability of virus shells to encapsulate a wide range of functional cargoes, especially multiple cargoes - siRNAs, enzymes, and chromophores - has made them an essential tool in…

physics.bio-ph2025

Impact of the RNA Binding Domain Localization of the Protein Shell on Virus Particle Stability

Mohammadamin Safdari, Siyu Li, Sanaz Panahandeh +2

The encapsulation of polyanions, whether single-stranded RNAs or synthetic polymers, is primarily driven by attractive electrostatic interactions between the positively charged, st…

cond-mat.soft2025★ 1 cited

General Solution for Elastic Networks on Arbitrary Curved Surfaces in the Absence of Rotational Symmetry

Yankang Liu, Siyu Li, Roya Zandi +1

Understanding crystal growth over arbitrary curved surfaces with arbitrary boundaries is a formidable challenge, stemming from the complexity of formulating non-linear elasticity u…

physics.bio-ph2024

Switchable Conformation in Protein Subunits: Unveiling Assembly Dynamics of Icosahedral Viruses

Siyu Li, Guillaume Tresset, Roya Zandi

The packaging of genetic material within a protein shell, called the capsid, marks a pivotal step in the life cycle of numerous single-stranded RNA viruses. Understanding how hundr…

cond-mat.soft2024

Dynamics of elongation of nematic tactoids in an electric field

Mohammadamin Safdari, Roya Zandi, Paul van der Schoot

Nematic tactoids are spindle-shaped droplets of a nematic phase nucleated in the co-existing isotropic phase. According to equilibrium theory, their internal structure and shape ar…

physics.bio-ph2022★ 37 cited

Biophysical Modeling of SARS-CoV-2 Assembly: Genome Condensation and Budding

Siyu Li, Roya Zandi

The COVID-19 pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has spurred unprecedented and concerted worldwide research to curtail and eradicate…