11 papers
Circulating Lymphocytes Preservation in Lung Cancer Stereotactic Body Radiation Therapy with Ultra-Fast Proton Delivery Using Modularized Pin Ridge Filters
Duncan Bohannon, Ahmal Jawad Zafar, Sibo Tian +9
Purpose: Radiation-induced lymphopenia is an increasingly recognized toxicity in lung radiotherapy and has been linked to radiation exposure to circulating lymphocytes (CL). In int…
A Digital Twin Framework for Adaptive Treatment Planning in Radiotherapy
Chih-Wei Chang, Sri Sai Akkineni, Mingzhe Hu +7
The development of a digital twin (DT) framework for fast online adaptive proton therapy planning in prostate stereotactic body radiation therapy (SBRT) with dominant intraprostati…
Optimizing Transmission FLASH Radiotherapy for Large-Field Post-Mastectomy Breast Treatment
Ahmal Jawad Zafar, Sunil William Dutta, Matthew Joseph Case +5
We investigated the effects of scanning speed, beam configuration, and dose-rate modeling on the FLASH effect in post-mastectomy proton transmission-beam (TB) planning and evaluate…
Foundation Models in Medical Image Analysis: A Systematic Review and Meta-Analysis
Praveenbalaji Rajendran, Mojtaba Safari, Wenfeng He +4
Recent advancements in artificial intelligence (AI), particularly foundation models (FMs), have revolutionized medical image analysis, demonstrating strong zero- and few-shot perfo…
Patient-Specific Deep Reinforcement Learning for Automatic Replanning in Head-and-Neck Cancer Proton Therapy
Malvern Madondo, Yuan Shao, Yingzi Liu +3
Anatomical changes during intensity-modulated proton therapy (IMPT) for head-and-neck cancer (HNC) can shift Bragg peaks, risking tumor underdosing and organ-at-risk overdosing. Tr…
Stereotactic Arrhythmia Radioablation for Refractory Ventricular Tachycardia: A Narrative Review and Exploratory Pooled Analysis of Clinical Outcomes and Toxicity
Keyur D. Shah, Chih-Wei Chang, Sibo Tian +6
Purpose: Stereotactic arrhythmia radioablation (STAR) is a non-invasive salvage therapy for refractory ventricular tachycardia (VT), especially in patients ineligible for catheter…