activity
20042020
most citedEffect of promoter architecture on the cell-to-cell variability in gene expression

172 citations · 423 across the 10 of their papers we have counts for

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Showing 2008Show all

2 papers · 1 filter

q-bio.BM2008★ 94 cited

Concentration and Length Dependence of DNA Looping in Transcriptional Regulation

Lin Han, Hernan G. Garcia, Seth Blumberg +4

In many cases, transcriptional regulation involves the binding of transcription factors at sites on the DNA that are not immediately adjacent to the promoter of interest. This acti…

q-bio.BM2008★ 8 cited

First-principles calculation of DNA looping in tethered particle experiments

Kevin B. Towles, John F. Beausang, Hernan G. Garcia +2

We calculate the probability of DNA loop formation mediated by regulatory proteins such as Lac repressor (LacI), using a mathematical model of DNA elasticity. Our model is adapted…