3 papers
physics.bio-ph2017
Gaussian curvature directs the distribution of spontaneous curvature on bilayer membrane necks
Morgan Chabanon, Padmini Rangamani
Formation of membrane necks is crucial for fission and fusion in lipid bilayers. In this work, we seek to answer the following fundamental question: what is the relationship betwee…
q-bio.MN2016
Shear-Induced Nitric Oxide Production by Endothelial Cells
Krishna Sriram, Justin G. Laughlin, Padmini Rangamani +1
We present a biochemical model of the wall shear stress (WSS)-induced activation of endothelial nitric oxide synthase (eNOS) in an endothelial cell (EC). The model includes three k…
physics.bio-ph2016
Membrane tension is a key determinant of bud morphology in clathrin-mediated endocytosis
Julian E. Hassinger, George Oster, David G. Drubin +1
In clathrin-mediated endocytosis (CME), clathrin and various adaptor proteins coat a patch of the plasma membrane, which is reshaped to form a budded vesicle. Experimental studies…