144 citations · 810 across the 34 of their papers we have counts for
36 papers
Synaptic spine head morphodynamics from graph grammar rules for actin dynamics
Matthew Hur, Thomas Bartol, Padmini Rangamani +2
There is a morphodynamic component to synaptic learning by which changes in dendritic (postsynaptic) spine head size are associated with the strengthening or weakening of the synap…
Modeling collagen fibril degradation as a function of matrix microarchitecture
B. Debnath, B. N. Narasimhan, S. I. Fraley +1
Collagenolytic degradation is a process fundamental to tissue remodeling. The microarchitecture of collagen fibril networks changes during development, aging, and disease. Such cha…
The evolution of systems biology and systems medicine: From mechanistic models to uncertainty quantification
Lingxia Qiao, Ali Khalilimeybodi, Nathaniel J Linden-Santangeli +1
Understanding the mechanisms of interactions within cells, tissues, and organisms is crucial to driving developments across biology and medicine. Mathematical modeling is an essent…
Increasing certainty in systems biology models using Bayesian multimodel inference
Nathaniel Linden-Santangeli, Jin Zhang, Boris Kramer +1
Mathematical models are indispensable to the system biology toolkit for studying the structure and behavior of intracellular signaling networks. A common approach to modeling is to…
Spatial modeling algorithms for reactions and transport (SMART) in biological cells
Emmet A. Francis, Justin G. Laughlin, Jørgen S. Dokken +4
Biological cells rely on precise spatiotemporal coordination of biochemical reactions to control their many functions. Such cell signaling networks have been a common focus for mat…
Interplay between cortical adhesion and membrane bending regulates microparticle formation
Arijit Mahapatra, Sage A. Malingen, Padmini Rangamani
The formation of microparticles requires the bending of the plasma membrane away from the cytosol. The capcity of the cell membrane to form a microparticle, and the rate of membran…