144 citations · 810 across the 34 of their papers we have counts for
3 papers · 1 filter
The evolution of systems biology and systems medicine: From mechanistic models to uncertainty quantification
Lingxia Qiao, Ali Khalilimeybodi, Nathaniel J Linden-Santangeli +1
Understanding the mechanisms of interactions within cells, tissues, and organisms is crucial to driving developments across biology and medicine. Mathematical modeling is an essent…
Shear-Induced Nitric Oxide Production by Endothelial Cells
Krishna Sriram, Justin G. Laughlin, Padmini Rangamani +1
We present a biochemical model of the wall shear stress (WSS)-induced activation of endothelial nitric oxide synthase (eNOS) in an endothelial cell (EC). The model includes three k…
ATP concentration regulates enzyme kinetics
Jasmine Nirody, Padmini Rangamani
Adenosine 5'-triphosphate (ATP) is the nearly ubiquitous "energy currency" of living organisms, and thus is a crucial participant in the majority of enzymatic reactions. The standa…