14 citations · 40 across the 8 of their papers we have counts for
9 papers
A minimal physical model for curvotaxis driven by curved protein complexes at the cell's leading edge
Raj Kumar Sadhu, Marine Luciano, Wang Xi +12
Cells often migrate on curved surfaces inside the body, such as curved tissues, blood vessels or highly curved protrusions of other cells. Recent \textit{in-vitro} experiments prov…
Coiling of cellular protrusions around extracellular fibers
Raj Kumar Sadhu, Christian Hernandez-Padilla, Yael Eshed Eisenbach +8
Protrusions at the leading-edge of a cell play an important role in sensing the extracellular cues, during cellular spreading and motility. Recent studies provided indications that…
Theoretical model of efficient phagocytosis driven by curved membrane proteins and active cytoskeleton forces
Raj Kumar Sadhu, Sarah R Barger, Samo Penič +4
Phagocytosis is the process of engulfment and internalization of comparatively large particles by the cell, that plays a central role in the functioning of our immune system. We st…
Modelling cellular spreading and emergence of motility in the presence of curved membrane proteins and active cytoskeleton forces
Raj Kumar Sadhu, Samo Penič, Aleš Iglič +1
Eukaryotic cells adhere to extracellular matrix during the normal development of the organism, forming static adhesion as well as during cell motility. We study this process by con…
Phase diagram of the repulsive Blume-Emery-Griffiths model in the presence of external magnetic field on a complete graph
Soheli Mukherjee, Raj Kumar Sadhu, Sumedha
For the repulsive Blume-Emery-Griffiths model the phase diagram in the space of three fields, temperature (T), crystal field (), and magnetic field (H), is computed on a complet…
Interplay between surface and bending energy helps membrane protrusion formation
Raj Kumar Sadhu, Sakuntala Chatterjee
We consider a one-dimensional elastic membrane, which is pushed by growing filaments. The filaments tend to grow by creating local protrusions in the membrane and this process has…
Actin filaments pushing against a barrier: Comparison between two force generation mechanisms
Raj Kumar Sadhu, Sakuntala Chatterjee
To theoretically understand force generation properties of actin filaments, many models consider growing filaments pushing against a movable obstacle or barrier. In order to grow,…
Actin filaments growing against an elastic membrane: Effect of membrane tension
Raj Kumar Sadhu, Sakuntala Chatterjee
We study the force generation by a set of parallel actin filaments growing against an elastic membrane. The elastic membrane tries to stay flat and any deformation from this flat s…
Actin filaments growing against a barrier with fluctuating shape
Raj Kumar Sadhu, Sakuntala Chatterjee
We study force generation by a set of parallel actin filaments growing against a non-rigid obstacle, in presence of an external load. The filaments polymerize by either moving the…