activity
20162022
most citedActin filaments growing against a barrier with fluctuating shape

12 citations · 15 across the 5 of their papers we have counts for

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physics.bio-ph2022

Coiling of cellular protrusions around extracellular fibers

Raj Kumar Sadhu, Christian Hernandez-Padilla, Yael Eshed Eisenbach +8

Protrusions at the leading-edge of a cell play an important role in sensing the extracellular cues, during cellular spreading and motility. Recent studies provided indications that…

physics.bio-ph2021

Modelling cellular spreading and emergence of motility in the presence of curved membrane proteins and active cytoskeleton forces

Raj Kumar Sadhu, Samo Penič, Aleš Iglič +1

Eukaryotic cells adhere to extracellular matrix during the normal development of the organism, forming static adhesion as well as during cell motility. We study this process by con…

physics.bio-ph2019

Interplay between surface and bending energy helps membrane protrusion formation

Raj Kumar Sadhu, Sakuntala Chatterjee

We consider a one-dimensional elastic membrane, which is pushed by growing filaments. The filaments tend to grow by creating local protrusions in the membrane and this process has…

physics.bio-ph20193 cited

Actin filaments pushing against a barrier: Comparison between two force generation mechanisms

Raj Kumar Sadhu, Sakuntala Chatterjee

To theoretically understand force generation properties of actin filaments, many models consider growing filaments pushing against a movable obstacle or barrier. In order to grow,…

physics.bio-ph2018

Actin filaments growing against an elastic membrane: Effect of membrane tension

Raj Kumar Sadhu, Sakuntala Chatterjee

We study the force generation by a set of parallel actin filaments growing against an elastic membrane. The elastic membrane tries to stay flat and any deformation from this flat s…