79 citations · 237 across the 20 of their papers we have counts for
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Optimized Treatment Schedules for Chronic Myeloid Leukemia
Qie He, Junfeng Zhu, David Dingli +2
Over the past decade, several targeted therapies (e.g. imatinib, dasatinib, nilotinib) have been developed to treat Chronic Myeloid Leukemia (CML). Despite an initial response to t…
Robust and probabilistic optimization of dose schedules in radiotherapy
Hamidreza Badri, Yoichi Watanabe, Kevin Leder
We consider the effects of parameter uncertainty on the optimal radiation schedule in the context of the linear-quadratic model. Our interest arises from the observation that if in…
Minimizing Metastatic Risk in Radiotherapy Fractionation Schedules
Hamidreza Badri, Jagdish Ramakrishnan, Kevin Leder
Metastasis is the process by which cells from a primary tumor disperse and form new tumors at distant anatomical locations. The treatment and prevention of metastatic cancer remain…