239 citations · 412 across the 24 of their papers we have counts for
5 papers · 1 filter
A mechanistic first--passage time framework for bacterial cell-division timing
Khem Raj Ghusinga, Cesar A. Vargas-Garcia, Abhyudai Singh
How exponentially growing cells maintain size homeostasis is an important fundamental problem. Recent single-cell studies in prokaryotes have uncovered the adder principle, where c…
Optimal regulation of protein degradation to schedule cellular events with precision
Khem Raj Ghusinga, Abhyudai Singh
An important occurrence in many cellular contexts is the crossing of a prescribed threshold by a regulatory protein. The timing of such events is stochastic as a consequence of the…
Decomposing variability in protein levels from noisy expression, genome duplication and partitioning errors during cell-divisions
Mohammad Soltani, Cesar Augusto Vargas-Garcia, Duarte Antunes +1
Inside individual cells, expression of genes is inherently stochastic and manifests as cell-to-cell variability or noise in protein copy numbers. Since proteins half-lives can be c…
Stochastic Analysis Of An Incoherent Feedforward Genetic Motif
Thierry Platini, Mohammad Soltani, Abhyudai Singh
Gene products (RNAs, proteins) often occur at low molecular counts inside individual cells, and hence are subject to considerable random fluctuations (noise) in copy number over ti…
Host-feeding enhances stability of discrete-time host-parasitoid population dynamic models
Brooks Emerick, Abhyudai Singh
Discrete-time models are the traditional approach for capturing population dynamics of a host-parasitoid system. Recent work has introduced a semi-discrete framework for obtaining…