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math.AP2026
A Single Equation Explains Go-or-Grow Dynamics in Cyclic Hypoxia
Gopinath Sadhu, Philip K Maini, Mohit Kumar Jolly
We propose a minimal mathematical framework to describe the go-or-grow dynamics of tumor cells comprising two phenotypically distinct populations. One population is migratory and u…
math.AP2023
An integrative phenotype-structured partial differential equation model for the population dynamics of epithelial-mesenchymal transition
Jules Guilberteau, Paras Jain, Mohit Kumar Jolly +2
Phenotypic heterogeneity along the epithelial-mesenchymal (E-M) axis contributes to cancer metastasis and drug resistance. Recent experimental efforts have collated detailed time-c…