205 citations · 210 across the 6 of their papers we have counts for
8 papers
Biophysical and Biochemical mechanisms underlying Collective Cell Migration in Cancer Metastasis
Ushasi Roy, Tyler Collins, Mohit K. Jolly +1
Multicellular collective migration is a ubiquitous strategy of cells to translocate spatially in diverse tissue environments to accomplish a wide variety of biological phenomena, v…
Towards decoding the coupled decision-making of metabolism and epithelial-mesenchymal transition in cancer
Dongya Jia, Jun Hyoung Park, Harsimran Kaur +9
Cancer cells have the plasticity to adjust their metabolic phenotypes for survival and metastasis. During metastasis, a developmental program known as the epithelial-mesenchymal tr…
Understanding the principles of pattern formation driven by Notch signaling by integrating experiments and theoretical models
Federico Bocci, Jose Nelson Onuchic, Mohit Kumar Jolly
Notch signaling is an evolutionary conserved cell-cell communication pathway. Besides regulating cell-fate decisions at an individual cell level, Notch signaling coordinates the em…
Mathematical Modeling of Plasticity and Heterogeneity in EMT
Shubham Tripathi, Jianhua Xing, Herbert Levine +1
Epithelial-Mesenchymal Transition (EMT), and the corresponding reverse process, Mesenchymal-Epithelial Transition (MET), are dynamic and reversible cellular programs orchestrated b…
Quantifying cancer epithelial-mesenchymal plasticity and its association with stemness and immune response
Dongya Jia, Xuefei Li, Federico Bocci +5
Cancer cells can acquire a spectrum of stable hybrid epithelial/mesenchymal (E/M) states during epithelial-mesenchymal transition (EMT). Cells in these hybrid E/M phenotypes often…
Deciphering the dynamics of Epithelial-Mesenchymal Transition and Cancer Stem Cells in tumor progression
Federico Bocci, Herbert Levine, José Nelson Onuchic +1
Purpose of review: The epithelial-Mesenchymal Transition (EMT) and the generation of Cancer Stem Cells (CSC) are two fundamental aspects contributing to tumor growth, acquisition o…