activity
20152026
most citedNanopore Sequencing Technology and Tools for Genome Assembly: Computational Analysis of the Current State, Bottlenecks and Future Directions

269 citations · 3.4k across the 186 of their papers we have counts for

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Showing q-bio.GNShow all

12 papers · 1 filter

q-bio.GN2022★ 12 cited

TargetCall: Eliminating the Wasted Computation in Basecalling via Pre-Basecalling Filtering

Meryem Banu Cavlak, Gagandeep Singh, Mohammed Alser +6

Basecalling is an essential step in nanopore sequencing analysis where the raw signals of nanopore sequencers are converted into nucleotide sequences, i.e., reads. State-of-the-art…

q-bio.GN2022

Going From Molecules to Genomic Variations to Scientific Discovery: Intelligent Algorithms and Architectures for Intelligent Genome Analysis

Mohammed Alser, Joel Lindegger, Can Firtina +5

We now need more than ever to make genome analysis more intelligent. We need to read, analyze, and interpret our genomes not only quickly, but also accurately and efficiently enoug…

q-bio.GN2022★ 6 cited

FastRemap: A Tool for Quickly Remapping Reads between Genome Assemblies

Jeremie S. Kim, Can Firtina, Meryem Banu Cavlak +3

A genome read data set can be quickly and efficiently remapped from one reference to another similar reference (e.g., between two reference versions or two similar species) using a…

q-bio.GN2021★ 39 cited

BLEND: A Fast, Memory-Efficient, and Accurate Mechanism to Find Fuzzy Seed Matches in Genome Analysis

Can Firtina, Jisung Park, Mohammed Alser +8

Generating the hash values of short subsequences, called seeds, enables quickly identifying similarities between genomic sequences by matching seeds with a single lookup of their h…

q-bio.GN2020★ 155 cited

Technology dictates algorithms: Recent developments in read alignment

Mohammed Alser, Jeremy Rotman, Kodi Taraszka +13

Massively parallel sequencing techniques have revolutionized biological and medical sciences by providing unprecedented insight into the genomes of humans, animals, and microbes. M…

q-bio.GN2019★ 4 cited

AirLift: A Fast and Comprehensive Technique for Remapping Alignments between Reference Genomes

Jeremie S. Kim, Can Firtina, Meryem Banu Cavlak +5

AirLift is the first read remapping tool that enables users to quickly and comprehensively map a read set, that had been previously mapped to one reference genome, to another simil…