143 citations · 1.5k across the 45 of their papers we have counts for
45 papers
Entropic Clustering of Stickers Induces Aging in Biocondensates
Hugo Le Roy, Paolo De Los Rios
Biomolecular condensates are cellular phase-separated droplets that usually exhibit a viscoelastic mechanical response. A behavior rationalized by modeling the complex molecules th…
Phase boundaries promote chemical reactions through localized fluxes
Alexandra Shelest, Hugo Le Roy, Daniel M. Busiello +1
One of the hypothesized functions of biomolecular condensates is to act as chemical reactors, where chemical reactions can be modulated, i.e. accelerated or slowed down, while subs…
Equilibrium and non-equilibrium furanose selection in the ribose isomerisation network
Avinash Vicholous Dass, Thomas Georgelin, Frances Westall +5
The exclusive presence of -D-ribofuranose in nucleic acids is still a conundrum in prebiotic chemistry, given that pyranose species are substantially more stable at equilibrium.…
Efficient conversion of chemical energy into mechanical work by Hsp70 chaperones
Salvatore Assenza, Alberto S. Sassi, Ruth Kellner +3
Hsp70 molecular chaperones are abundant ATP-dependent nanomachines that actively reshape non-native, misfolded proteins and assist a wide variety of essential cellular processes. H…
Entropic selection of concepts unveils hidden topics in documents corpora
Andrea Martini, Alessio Cardillo, Paolo De Los Rios
The organization and evolution of science has recently become itself an object of scientific quantitative investigation, thanks to the wealth of information that can be extracted f…
Thermodynamic bounds on the ultra- and infra-affinity of Hsp70 for its substrates
Basile Nguyen, David Hartich, Udo Seifert +1
The 70 kDa Heat Shock Proteins Hsp70 have several essential functions in living systems, such as protecting cells against protein aggregation, assisting protein folding, remodeling…