143 citations · 1.5k across the 45 of their papers we have counts for
4 papers · 1 filter
Efficient conversion of chemical energy into mechanical work by Hsp70 chaperones
Salvatore Assenza, Alberto S. Sassi, Ruth Kellner +3
Hsp70 molecular chaperones are abundant ATP-dependent nanomachines that actively reshape non-native, misfolded proteins and assist a wide variety of essential cellular processes. H…
Thermodynamic bounds on the ultra- and infra-affinity of Hsp70 for its substrates
Basile Nguyen, David Hartich, Udo Seifert +1
The 70 kDa Heat Shock Proteins Hsp70 have several essential functions in living systems, such as protecting cells against protein aggregation, assisting protein folding, remodeling…
Discrete breathers in nonlinear network models of proteins
Brice Juanico, Yves-Henri Sanejouand, Francesco Piazza +1
We introduce a topology-based nonlinear network model of protein dynamics with the aim of investigating the interplay of spatial disorder and nonlinearity. We show that spontaneous…
Functional Dynamics of PDZ Binding Domains: A Normal Mode Analysis
Paolo De Los Rios, Fabio Cecconi, Anna Pretre +4
PDZ (Post-synaptic density-95/discs large/zonula occludens-1) domains are relatively small (80 to 120 residues) protein binding modules central in the organization of receptor clus…