activity
20122021
most citedDiscrete and continuum models for the evolutionary and spatial dynamics of cancer: a very short introduction through two case studies

7 citations · 7 across the 2 of their papers we have counts for

collaborators

15 papers

math.AP2021

Effective interface conditions for continuum mechanical models describing the invasion of multiple cell populations through thin membranes

Chiara Giverso, Tommaso Lorenzi, Luigi Preziosi

We consider a continuum mechanical model for the migration of multiple cell populations through parts of tissue separated by thin membranes. In this model, cells belonging to diffe…

q-bio.TO2020

A mathematical study of the influence of hypoxia and acidity on the evolutionary dynamics of cancer

Giada Fiandaca, Marcello Delitala, Tommaso Lorenzi

Hypoxia and acidity act as environmental stressors promoting selection for cancer cells with a more aggressive phenotype. As a result, a deeper theoretical understanding of the spa…

q-bio.CB2020

A hybrid discrete-continuum approach to model Turing pattern formation

Fiona R Macfarlane, Mark AJ Chaplain, Tommaso Lorenzi

Since its introduction in 1952, Turing's (pre-)pattern theory ("the chemical basis of morphogenesis") has been widely applied to a number of areas in developmental biology. The rel…

math.AP2019

From a discrete model of chemotaxis with volume-filling to a generalised Patlak-Keller-Segel model

Federica Bubba, Tommaso Lorenzi, Fiona R Macfarlane

We present a discrete model of chemotaxis whereby cells responding to a chemoattractant are seen as individual agents whose movement is described through a set of rules that result…

q-bio.TO2019

Evolutionary dynamics in vascularised tumours under chemotherapy

Chiara Villa, Mark A. J. Chaplain, Tommaso Lorenzi

We consider a mathematical model for the evolutionary dynamics of tumour cells in vascularised tumours under chemotherapy. The model comprises a system of coupled partial integro-d…

q-bio.TO20197 cited

Discrete and continuum models for the evolutionary and spatial dynamics of cancer: a very short introduction through two case studies

Tommaso Lorenzi, Fiona R. Macfarlane, Chiara Villa

We give a very short introduction to discrete and continuum models for the evolutionary and spatial dynamics of cancer through two case studies: a model for the evolutionary dynami…