34 citations · 226 across the 27 of their papers we have counts for
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A hybrid discrete-continuum modelling approach to explore the impact of T-cell infiltration on anti-tumour immune response
Luis Almeida, Chloe Audebert, Emma Leschiera +1
We present a spatial hybrid discrete-continuum modelling framework for the interaction dynamics between tumour cells and cytotoxic T cells, which play a pivotal role in the immune…
The impact of phenotypic heterogeneity on chemotactic self-organisation
Fiona R Macfarlane, Tommaso Lorenzi, Kevin J Painter
The capacity to aggregate through chemosensitive movement forms a paradigm of self-organisation, with examples spanning cellular and animal systems. A basic mechanism assumes a phe…
Individual-based and continuum models of phenotypically heterogeneous growing cell populations
Fiona R Macfarlane, Xinran Ruan, Tommaso Lorenzi
Existing studies comparing individual-based models of growing cell populations and their continuum counterparts have mainly focused on homogeneous populations, in which all cells h…