221 citations · 932 across the 42 of their papers we have counts for
4 papers · 1 filter
Quantifying uniformity of mapped reads
Valerie Hower, Richard Starfield, Adam Roberts +1
Summary: We describe a tool for quantifying the uniformity of mapped reads in high-throughput sequencing experiments. Our statistic directly measures the uniformity of both read po…
RNA structure characterization from chemical mapping experiments
Sharon Aviran, Julius B. Lucks, Lior Pachter
Despite great interest in solving RNA secondary structures due to their impact on function, it remains an open problem to determine structure from sequence. Among experimental appr…
Models for transcript quantification from RNA-Seq
Lior Pachter
RNA-Seq is rapidly becoming the standard technology for transcriptome analysis. Fundamental to many of the applications of RNA-Seq is the quantification problem, which is the accur…
Affine and Projective Tree Metric Theorems
Aaron Kleinman, Matan Harel, Lior Pachter
The tree metric theorem provides a combinatorial four point condition that characterizes dissimilarity maps derived from pairwise compatible split systems. A similar (but weaker) f…