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Reconstructing the Population Genetic History of the Caribbean
Andres Moreno-Estrada, Simon Gravel, Fouad Zakharia +18
The Caribbean basin is home to some of the most complex interactions in recent history among previously diverged human populations. Here, by making use of genome-wide SNP array dat…
Reconstructing Native American Migrations from Whole-genome and Whole-exome Data
Simon Gravel, Fouad Zakharia, Andres Moreno-Estrada +17
There is great scientific and popular interest in understanding the genetic history of populations in the Americas. We wish to understand when different regions of the continent we…
Genetic recombination is targeted towards gene promoter regions in dogs
Adam Auton, Ying Rui Li, Jeffrey Kidd +9
The identification of the H3K4 trimethylase, PRDM9, as the gene responsible for recombination hotspot localization has provided considerable insight into the mechanisms by which re…
The genetic prehistory of southern Africa
Joseph K. Pickrell, Nick Patterson, Chiara Barbieri +18
Southern and eastern African populations that speak non-Bantu languages with click consonants are known to harbour some of the most ancient genetic lineages in humans, but their re…
Inferring the joint demographic history of multiple populations from multidimensional SNP frequency data
Ryan N. Gutenkunst, Ryan D. Hernandez, Scott H. Williamson +1
Demographic models built from genetic data play important roles in illuminating prehistorical events and serving as null models in genome scans for selection. We introduce an infer…