activity
20072011
most citedSingle-molecule derivation of salt dependent base-pair free energies in DNA

258 citations · 565 across the 5 of their papers we have counts for

collaborators

5 papers

cond-mat.stat-mech2011★ 7 cited

A robust approach to estimating rates from time-correlation functions

John D. Chodera, Phillip J. Elms, William C. Swope +5

While seemingly straightforward in principle, the reliable estimation of rate constants is seldom easy in practice. Numerous issues, such as the complication of poor reaction coord…

physics.bio-ph2010★ 258 cited

Single-molecule derivation of salt dependent base-pair free energies in DNA

J. M. Huguet, C. V. Bizarro, N. Forns +3

Accurate knowledge of the thermodynamic properties of nucleic acids is crucial to predicting their structure and stability. To date most measurements of base-pair free energies in…

physics.bio-ph2007★ 80 cited

Force unfolding kinetics of RNA using optical tweezers. II. Modeling experiments

M. Manosas, J. -D. Wen, P. T. X. Li +4

By exerting mechanical force it is possible to unfold/refold RNA molecules one at a time. In a small range of forces, an RNA molecule can hop between the folded and the unfolded st…

physics.bio-ph2007★ 152 cited

Force unfolding kinetics of RNA using optical tweezers. I. Effects of experimental variables on measured results

J. -D. Wen, M. Manosas, P. T. X. Li +4

Experimental variables of optical tweezers instrumentation that affect RNA folding/unfolding kinetics were investigated. A model RNA hairpin, P5ab, was attached to two micron-sized…

cond-mat.stat-mech2007★ 68 cited

Bayesian estimates of free energies from nonequilibrium work data in the presence of instrument noise

Paul Maragakis, Felix Ritort, Carlos Bustamante +2

The Jarzynski equality and the fluctuation theorem relate equilibrium free energy differences to non-equilibrium measurements of the work. These relations extend to single-molecule…