1.9k citations · 4.7k across the 18 of their papers we have counts for
18 papers
Granger causal inference on DAGs identifies genomic loci regulating transcription
Rohit Singh, Alexander P. Wu, Bonnie Berger
When a dynamical system can be modeled as a sequence of observations, Granger causality is a powerful approach for detecting predictive interactions between its variables. However,…
Explicitly disentangling image content from translation and rotation with spatial-VAE
Tristan Bepler, Ellen D. Zhong, Kotaro Kelley +2
Given an image dataset, we are often interested in finding data generative factors that encode semantic content independently from pose variables such as rotation and translation.…
Reconstructing continuous distributions of 3D protein structure from cryo-EM images
Ellen D. Zhong, Tristan Bepler, Joseph H. Davis +1
Cryo-electron microscopy (cryo-EM) is a powerful technique for determining the structure of proteins and other macromolecular complexes at near-atomic resolution. In single particl…
Learning protein sequence embeddings using information from structure
Tristan Bepler, Bonnie Berger
Inferring the structural properties of a protein from its amino acid sequence is a challenging yet important problem in biology. Structures are not known for the vast majority of p…
Fast Characterization of Segmental Duplications in Genome Assemblies
Ibrahim Numanagić, Alim S. Gökkaya, Lillian Zhang +3
Segmental duplications (SDs), or low-copy repeats (LCR), are segments of DNA greater than 1 Kbp with high sequence identity that are copied to other regions of the genome. SDs are…
Large-Margin Classification in Hyperbolic Space
Hyunghoon Cho, Benjamin DeMeo, Jian Peng +1
Representing data in hyperbolic space can effectively capture latent hierarchical relationships. With the goal of enabling accurate classification of points in hyperbolic space whi…