2 citations · 4 across the 7 of their papers we have counts for
7 papers · 1 filter
Factors that Affect the Folding Ability of Proteins
Aaron R. Dinner, Victor Abkevich, Eugene Shakhnovich +1
The folding ability of a heteropolymer model for proteins subject to Monte Carlo dynamics on a simple cubic lattice is shown to be strongly correlated with the energy gap between t…
Protein design: A perspective from simple tractable models
E. I. Shakhnovich
We review the recent progress in computational approaches to protein design which builds on advances in statistical-mechanical protein folding theory. In particular, we evaluate th…
How to derive a protein folding potential? A new approach to the old problem
L. A. Mirny, E. I. Shakhnovich
In this paper we introduce a novel method of deriving a pairwise potential for protein folding. The potential is obtained by optimization procedure, which simultaneously maximizes…
Theory of Kinetic Partitioning in Protein Folding (With Application to Prions)
V. I. Abkevich, A. M. Gutin, E. I. Shakhnovich
In this paper we study the phenomenon of kinetic partitioning when a polypeptide chain has two ground state conformations one of which is more kinetically reachable than the other.…
Cooperativity of Protein Folding and the Random-Field Ising Model
A. M. Gutin, V. I. Abkevich, E. I. Shakhnovich
The relation between cooperativity of protein folding and the Random-Field Ising Model (RFIM) is established. Generalization of the Imry-Ma argument predicts cooperative folding tr…
Statistical mechanics of a cross-linked polymer blend
C. D. Sfatos, A. M. Gutin, E. I. Shakhnovich
We study a blend of two kinds of homopolymers with tendency for segragation. Cross-links between the chains of different kinds do not allow macrophase separation. Instead microphas…