326 citations · 563 across the 5 of their papers we have counts for
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q-bio.BM2006★ 326 cited
Protein and DNA sequence determinants of thermophilic adaptation
Konstantin B. Zeldovich, Igor N. Berezovsky, Eugene I. Shakhnovich
Prokaryotes living at extreme environmental temperatures exhibit pronounced signatures in the amino acid composition of their proteins and nucleotide compositions of their genomes…
q-bio.BM2006★ 142 cited
Positive and negative design in stability and thermal adaptation of natural proteins
Igor N. Berezovsky, Konstantin B. Zeldovich, Eugene I. Shakhnovich
The aim of this work is to elucidate how physical principles of protein design are reflected in natural sequences that evolved in response to the thermal conditions of the environm…