326 citations · 563 across the 5 of their papers we have counts for
Showing 2005Show all
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q-bio.GN2005
Physical origins of protein superfamilies
Konstantin B. Zeldovich, Igor N. Berezovsky, Eugene I. Sha
In this work, we discovered a fundamental connection between selection for protein stability and emergence of preferred structures of proteins. Using standard exact 3-dimensional l…
q-bio.BM2005★ 94 cited
Entropic stabilization of proteins and its proteomic consequences
Igor N. Berezovsky, William W. Chen, Paul J. Choi +1
We report here a new entropic mechanism of protein thermostability due to residual dynamics of rotamer isomerization in native state. All-atom simulations show that Lysines have mu…