587 citations · 1.4k across the 36 of their papers we have counts for
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The look-ahead effect of phenotypic mutations
Dion J. Whitehead, Claus O. Wilke, David Vernazobres +1
The evolution of complex molecular traits such as disulphide bridges often requires multiple mutations. The intermediate steps in such evolutionary trajectories are likely to be se…
The traveling wave approach to asexual evolution: Muller's ratchet and speed of adaptation
Igor M. Rouzine, Eric Brunet, Claus O. Wilke
We use traveling-wave theory to derive expressions for the rate of accumulation of deleterious mutations under Muller's ratchet and the speed of adaptation under positive selection…
The stochastic edge in adaptive evolution
Eric Brunet, Igor M. Rouzine, Claus O. Wilke
In a recent article, Desai and Fisher (2007) proposed that the speed of adaptation in an asexual population is determined by the dynamics of the stochastic edge of the population,…