587 citations · 1.4k across the 36 of their papers we have counts for
Showing 2004Show all
3 papers · 1 filter
q-bio.PE2004★ 5 cited
Tradeoff between short-term and long-term adaptation in a changing environment
Robert Forster, Claus O. Wilke
We investigate the competition dynamics of two microbial or viral strains that live in an environment that switches periodically between two states. One of the strains is adapted t…
q-bio.PE2004
Replication at periodically changing multiplicity of infection promotes stable coexistence of competing viral populations
Claus O. Wilke, Daniel D. Reissig, Isabel S. Novella
RNA viruses are a widely used tool to study evolution experimentally. Many standard protocols of virus propagation and competition are done at nominally low multiplicity of infecti…
q-bio.PE2004
The Speed of Adaptation in Large Asexual Populations
Claus O. Wilke
In large asexual populations, beneficial mutations have to compete with each other for fixation. Here, I derive explicit analytic expressions for the rate of substitution and the m…