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physics.bio-ph2000★ 17 cited
Dynamic fitness landscapes: Expansions for small mutation rates
Claus Wilke, Christopher Ronnewinkel
We study the evolution of asexual microorganisms with small mutation rate in fluctuating environments, and develop techniques that allow us to expand the formal solution of the evo…
physics.bio-ph2000
Interaction between directional epistasis and average mutational effects
Claus O. Wilke, Christoph Adami
We investigate the relationship between the average fitness decay due to single mutations and the strength of epistatic interactions in genetic sequences. We observe that epistatic…