activity
20102018
most citedEnzyme-Based Logic: OR Gate with Double-Sigmoid Filter Response

58 citations · 368 across the 11 of their papers we have counts for

collaborators
Showing 2013Show all

8 papers · 1 filter

q-bio.MN2013★ 48 cited

Networked Enzymatic Logic Gates with Filtering: New Theoretical Modeling Expressions and Their Experimental Application

Vladimir Privman, Oleksandr Zavalov, Lenka Halamkova +3

We report the first study of a network of connected enzyme-catalyzed reactions, with added chemical and enzymatic processes that incorporate the recently developed biochemical filt…

cond-mat.soft2013★ 43 cited

Enzymatic AND Logic Gate with Sigmoid Response Induced by Photochemically Controlled Oxidation of the Output

Vladimir Privman, Brian E. Fratto, Oleksandr Zavalov +2

We report a study of a system which involves an enzymatic cascade realizing an AND logic gate, with an added photochemical processing of the output allowing to make the gate's resp…

physics.bio-ph2013★ 38 cited

Modularity of Biochemical Filtering for Inducing Sigmoid Response in Both Inputs in an Enzymatic AND Gate

Saira Bakshi, Oleksandr Zavalov, Jan Halamek +2

We report the first systematic study of designed two-input biochemical systems as information processing gates with favorable noise-transmission properties accomplished by modifyin…

physics.bio-ph2013

Two-Input Enzymatic Logic Gates Made Sigmoid by Modifications of the Biocatalytic Reaction Cascades

Oleksandr Zavalov, Vera Bocharova, Jan Halamek +6

Computing based on biochemical processes is a newest rapidly developing field of unconventional information and signal processing. In this paper we present results of our research…

q-bio.MN2013★ 7 cited

Extended Linear Response for Bioanalytical Applications Using Multiple Enzymes

Vladimir Privman, Oleksandr Zavalov, Aleksandr Simonian

We develop a framework for optimizing a novel approach to extending the linear range of bioanalytical systems and biosensors by utilizing two enzymes with different kinetic respons…

q-bio.MN2013★ 58 cited

Enzyme-Based Logic: OR Gate with Double-Sigmoid Filter Response

Oleksandr Zavalov, Vera Bocharova, Vladimir Privman +1

The first realization of a biomolecular OR gate function with double-sigmoid response (sigmoid in both inputs) is reported. Two chemical inputs activate the enzymatic gate processe…