113 citations · 409 across the 12 of their papers we have counts for
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q-bio.MN2016★ 1 cited
Exploiting synthetic lethal vulnerabilities for cancer therapy
Sriganesh Srihari
Synthetic lethality refers to a combination of two or more genetic events (typically affecting different genes) in which the co-occurrence of the events results in cell or organism…
q-bio.MN2016★ 31 cited
Understanding the functional impact of copy number alterations in breast cancer using a network modeling approach
Sriganesh Srihari, Murugan Kalimutho, Samir Lal +5
Copy number alterations (CNAs) are thought to account for 85% of the variation in gene expression observed among breast tumours. The expression of cis-associated genes is impacted…