113 citations · 409 across the 12 of their papers we have counts for
4 papers · 1 filter
Evolution and Controllability of Cancer Networks: a Boolean Perspective
Sriganesh Srihari, Venkatesh Raman, Hon Wai Leong +1
Cancer forms a robust system and progresses as stages over time typically with increasing aggressiveness and worsening prognosis. Characterizing these stages and identifying the ge…
Identifying conserved protein complexes between species by constructing interolog networks
Phi Vu Nguyen, Sriganesh Srihari, Hon Wai Leong
Protein complexes conserved across species indicate processes that are core to cellular machinery (e.g. cell-cycle or DNA damage-repair complexes conserved across human and yeast).…
Computing Pathways to Systems Biology: Key Contributions of Computational Methods in Pathway Identification
Sriganesh Srihari, Mark A. Ragan
Understanding large molecular networks consisting of entities such as genes, proteins or RNAs that interact in complex ways to drive the cellular machinery has been an active focus…
Employing functional interactions for characterization and detection of sparse complexes from yeast PPI networks
Sriganesh Srihari, Hon Wai Leong
Over the last few years, several computational techniques have been devised to recover protein complexes from the protein interaction (PPI) networks of organisms. These techniques…