David A. Sivak

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20242026

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physics.bio-ph2025

Multiparameter optimal control of F1-ATPase

W. Callum Wareham, David A. Sivak

Biological molecular machines convert free energy between different forms in cells, often at high efficiency. Optimal control theory provides a framework to elucidate design princi…

physics.bio-ph2025

Efficiently driving F $_{1}$ molecular motor in experiment by suppressing nonequilibrium variation

Takahide Mishima, Deepak Gupta, Yohei Nakayama +4

F $_{1}$ -ATPase (F $_{1}$ ) is central to cellular energy transduction. Forcibly rotated by another motor F $_{o}$ , F $_{1}$ catalyzes ATP synthesis by converting mechanical work into…

Multiparameter optimal control of F1-ATPase

Efficiently driving F1​ molecular motor in experiment by suppressing nonequilibrium variation

Efficiently driving F $_{1}$ molecular motor in experiment by suppressing nonequilibrium variation