5 papers
Thermodynamic geometry of friction on graphs: Resistance, commute times, and optimal transport
Jordan R Sawchuk, David A Sivak
We demonstrate that the thermodynamic friction metric governing dissipation in slowly driven continuous-time Markov chains is equivalent to the commute-time embedding and the resis…
Effects of symmetry on coupled rotary molecular motors
Sara Iranbakhsh, David A. Sivak
As engineering advances toward the nanoscale, understanding design principles for molecular motors becomes increasingly valuable. Many molecular motors consist of coupled component…
Global thermodynamic manifold for conservative control of stochastic systems
Jordan R. Sawchuk, David A. Sivak
Optimal control of stochastic systems plays a central role in nonequilibrium physics, with applications in the study of biological molecular motors and the design of single-molecul…
Multiparameter optimal control of F1-ATPase
W. Callum Wareham, David A. Sivak
Biological molecular machines convert free energy between different forms in cells, often at high efficiency. Optimal control theory provides a framework to elucidate design princi…
Efficiently driving F molecular motor in experiment by suppressing nonequilibrium variation
Takahide Mishima, Deepak Gupta, Yohei Nakayama +4
F-ATPase (F) is central to cellular energy transduction. Forcibly rotated by another motor F, F catalyzes ATP synthesis by converting mechanical work into…