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Optical characterization of red blood cells from individuals with sickle cell trait and disease in Tanzania using quantitative phase imaging
JaeHwang Jung, Lucas E. Matemba, KyeoReh Lee +6
Sickle cell disease (SCD) is common across Sub-Saharan Africa. However, the investigation of SCD in this area has been significantly limited mainly due to the lack of research faci…
Label-free optical quantification of structural alterations in Alzheimer's disease
Moosung Lee, Eeksung Lee, JaeHwang Jung +5
We present a quantitative label-free imaging of mouse whole brain tissue slices with sub-micrometre resolution, employing holographic microscopy and an automated scanning platform.…
In vivo deep tissue imaging using wavefront shaping optical coherence tomography
Hyeonseung Yu, Jaehyun Peter Lee, KyeoReh Lee +5
Multiple light scattering in tissue limits the penetration of optical coherence tomography (OCT) imaging. Here, we present in-vivo OCT imaging of a live mouse using wavefront shapi…
Alterations in cell surface area and deformability of individual human red blood cells in stored blood
HyunJoo Park, Misook Ji, SangYun Lee +4
The functionality and viability of stored human red blood cells (RBCs) is an important clinical issue in transfusion. To systematically investigate changes in stored whole blood, t…
3-D refractive index tomograms and deformability of individual human red blood cells from cord blood of newborn infants and maternal blood
HyunJoo Park, Taegyu Ahnb, Kyoohyun Kim +6
Red blood cells (RBCs) from the cord blood of newborn infants have distinctive functions for fetal and infant development. To systematically investigate the biophysical characteris…