179 citations · 635 across the 21 of their papers we have counts for
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q-bio.CB2025
Mechanical activity enables patterning and discrimination at the immune synapse
Tony Wong, Tom Chou, Suraj Shankar +1
Immune cells recognize and discriminate antigens through immunological synapses - dynamic intercellular junctions exhibiting highly organized receptor-ligand patterns. While much w…
q-bio.CB2022★ 27 cited
Immune cells use active tugging forces to distinguish affinity and accelerate evolution
Hongda Jiang, Shenshen Wang
Cells are known to exert forces to sense their physical surroundings for guidance of motion and fate decisions. Here, we propose that cells might do mechanical work to drive their…