179 citations · 635 across the 21 of their papers we have counts for
21 papers
Mechanical activity enables patterning and discrimination at the immune synapse
Tony Wong, Tom Chou, Suraj Shankar +1
Immune cells recognize and discriminate antigens through immunological synapses - dynamic intercellular junctions exhibiting highly organized receptor-ligand patterns. While much w…
Adaptive mechanical proofreading toward faithful clonal selection
Qing Xu, Shenshen Wang
To ensure faithful information transmission, cells utilize nonequilibrium drives to reduce errors. Kinetic proofreading is a classic mechanism known to sharpen ligand discriminatio…
Migration feedback induces emergent ecotypes and abrupt transitions in evolving populations
Casey O. Barkan, Shenshen Wang
We explore the connection between migration patterns and emergent behaviors of evolving populations in spatially heterogeneous environments. Despite extensive studies in ecological…
Multiple Phase Transitions Shape Biodiversity of a Migrating Population
Casey Barkan, Shenshen Wang
In a wide variety of natural systems, closely-related microbial strains coexist stably, resulting in high levels of fine-scale biodiversity. However, the mechanisms that stabilize…
Effective Dynamics of Generative Adversarial Networks
Steven Durr, Youssef Mroueh, Yuhai Tu +1
Generative adversarial networks (GANs) are a class of machine-learning models that use adversarial training to generate new samples with the same (potentially very complex) statist…
Molecular tug of war reveals adaptive potential of an immune cell repertoire
Hongda Jiang, Shenshen Wang
The adaptive immune system constantly remodels its lymphocyte repertoire for better protection against future pathogens. Its ability to improve antigen recognition on the fly relie…