37 citations · 75 across the 30 of their papers we have counts for
3 papers · 1 filter
A Permutation Test for Assessing the Presence of Individual Differences in Treatment Effects
Chi Chang, Thomas Jaki, Muhammad Saad Sadiq +7
One size fits all approaches to medicine have become a thing of the past as the understanding of individual differences grows. The paper introduces a test for the presence of heter…
A Bayesian hierarchical model for bridging across patient subgroups in phase I clinical trials with animal data
Haiyan Zheng, Lisa V. Hampson, Thomas Jaki
Incorporating preclinical animal data, which can be regarded as a special kind of historical data, into phase I clinical trials can improve decision making when very little about h…
Estimation of treatment effects following a sequential trial of multiple treatments
John Whitehead, Yasin Desai, Thomas Jaki
When a clinical trial is subject to a series of interim analyses as a result of which the study may be terminated or modified, final frequentist analyses need to take account of th…