37 citations · 75 across the 30 of their papers we have counts for
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stat.ME2018
Improving Safety of the Continual Reassessment Method via a Modified Allocation Rule
Pavel Mozgunov, Thomas Jaki
This paper proposes a novel criterion for the allocation of patients in Phase~I dose-escalation clinical trials aiming to find the maximum tolerated dose (MTD). Conventionally, usi…
stat.ME2018★ 37 cited
An information-theoretic Phase I/II design for molecularly targeted agents that does not require an assumption of monotonicity
Pavel Mozgunov, Thomas Jaki
For many years Phase I and Phase II clinical trials were conducted separately, but there was a recent shift to combine these Phases. While a variety of Phase~I/II model-based desig…