165 citations · 243 across the 12 of their papers we have counts for
3 papers · 1 filter
Connecting Instrumental Variable methods for causal inference to the Estimand Framework
Jack Bowden, Bjoern Bornkamp, Ekkehard Glimm +1
Causal inference methods are gaining increasing prominence in pharmaceutical drug development in light of the recently published addendum on estimands and sensitivity analysis in c…
Graphical approaches for the control of generalised error rates
David S. Robertson, James M. S. Wason, Frank Bretz
When simultaneously testing multiple hypotheses, the usual approach in the context of confirmatory clinical trials is to control the familywise error rate (FWER), which bounds the…
Clinical trials impacted by the COVID-19 pandemic: Adaptive designs to the rescue?
Cornelia Ursula Kunz, Silke Jörgens, Frank Bretz +6
Very recently the new pathogen severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified and the coronavirus disease 2019 (COVID-19) declared a pandemic by the Wo…