75 citations · 177 across the 11 of their papers we have counts for
4 papers · 1 filter
Bayesian Semiparametric Estimation of Cancer-specific Age-at-onset Penetrance with Application to Li-Fraumeni Syndrome
Seung Jun Shin, Ying Yuan, Louise C. Strong +2
Penetrance, which plays a key role in genetic research, is defined as the proportion of individuals with the genetic variants (i.e., {genotype}) that cause a particular trait and w…
Bayesian data augmentation dose finding with continual reassessment method and delayed toxicity
Suyu Liu, Guosheng Yin, Ying Yuan
A major practical impediment when implementing adaptive dose-finding designs is that the toxicity outcome used by the decision rules may not be observed shortly after the initiatio…
Bayesian modeling longitudinal dyadic data with nonignorable dropout, with application to a breast cancer study
Guangyu Zhang, Ying Yuan
Dyadic data are common in the social and behavioral sciences, in which members of dyads are correlated due to the interdependence structure within dyads. The analysis of longitudin…
Bayesian phase I/II adaptively randomized oncology trials with combined drugs
Ying Yuan, Guosheng Yin
We propose a new integrated phase I/II trial design to identify the most efficacious dose combination that also satisfies certain safety requirements for drug-combination trials. W…