71 citations · 71 across the 1 of their papers we have counts for
2 papers
q-bio.BM2023
Improving Protein Optimization with Smoothed Fitness Landscapes
Andrew Kirjner, Jason Yim, Raman Samusevich +4
The ability to engineer novel proteins with higher fitness for a desired property would be revolutionary for biotechnology and medicine. Modeling the combinatorially large space of…
cs.LG2023★ 71 cited
SE(3) diffusion model with application to protein backbone generation
Jason Yim, Brian L. Trippe, Valentin De Bortoli +4
The design of novel protein structures remains a challenge in protein engineering for applications across biomedicine and chemistry. In this line of work, a diffusion model over ri…