22 citations · 22 across the 1 of their papers we have counts for
4 papers
Generative Flows on Discrete State-Spaces: Enabling Multimodal Flows with Applications to Protein Co-Design
Andrew Campbell, Jason Yim, Regina Barzilay +2
Combining discrete and continuous data is an important capability for generative models. We present Discrete Flow Models (DFMs), a new flow-based model of discrete data that provid…
Improved motif-scaffolding with SE(3) flow matching
Jason Yim, Andrew Campbell, Emile Mathieu +9
Protein design often begins with the knowledge of a desired function from a motif which motif-scaffolding aims to construct a functional protein around. Recently, generative models…
Fast non-autoregressive inverse folding with discrete diffusion
John J. Yang, Jason Yim, Regina Barzilay +1
Generating protein sequences that fold into a intended 3D structure is a fundamental step in de novo protein design. De facto methods utilize autoregressive generation, but this es…
Fast protein backbone generation with SE(3) flow matching
Jason Yim, Andrew Campbell, Andrew Y. K. Foong +8
We present FrameFlow, a method for fast protein backbone generation using SE(3) flow matching. Specifically, we adapt FrameDiff, a state-of-the-art diffusion model, to the flow-mat…