2 papers
q-bio.QM2025
Hierarchical protein backbone generation with latent and structure diffusion
Jason Yim, Marouane Jaakik, Ge Liu +5
We propose a hierarchical protein backbone generative model that separates coarse and fine-grained details. Our approach called LSD consists of two stages: sampling latents which a…
q-bio.BM2025
ProtComposer: Compositional Protein Structure Generation with 3D Ellipsoids
Hannes Stark, Bowen Jing, Tomas Geffner +4
We develop ProtComposer to generate protein structures conditioned on spatial protein layouts that are specified via a set of 3D ellipsoids capturing substructure shapes and semant…