76 citations · 161 across the 17 of their papers we have counts for
3 papers · 1 filter
Moduli Spaces of Phylogenetic Trees Describing Tumor Evolutionary Patterns
Sakellarios Zairis, Hossein Khiabanian, Andrew J. Blumberg +1
Cancers follow a clonal Darwinian evolution, with fitter subclones replacing more quiescent cells, ultimately giving rise to macroscopic disease. High-throughput genomics provides…
Parametric Inference using Persistence Diagrams: A Case Study in Population Genetics
Kevin Emmett, Daniel Rosenbloom, Pablo Camara +1
Persistent homology computes topological invariants from point cloud data. Recent work has focused on developing statistical methods for data analysis in this framework. We show th…
Characterizing Scales of Genetic Recombination and Antibiotic Resistance in Pathogenic Bacteria Using Topological Data Analysis
Kevin J. Emmett, Raul Rabadan
Pathogenic bacteria present a large disease burden on human health. Control of these pathogens is hampered by rampant lateral gene transfer, whereby pathogenic strains may acquire…